Eupenifeldin |
| Catalog No.GC43643 |
L'eupénifeldine est une bistropolone pentacyclique isolée À partir de cultures d'Eupenicillium brefeldianum ATCC 74184. L'eupénifeldine est cytotoxique contre la lignée cellulaire HCT-116. Eupenifeldin a le potentiel pour la recherche de la leucémie.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 151803-45-1
Sample solution is provided at 25 µL, 10mM.
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Eupenifeldin is a pentacyclic bistropolone fungal metabolite originally isolated from E. brefeldianum ATCC 74184. It is cytotoxic against HCT116 and HCTVM46 colon carcinoma cells in vitro (IC50s = 0.005 and 0.002 μg/ml, respectively). In vivo, eupenifeldin (0.3-2 mg/kg per day) increases median survival time in a mouse model of P388 leukemia.
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