RU-301 |
Catalog No.GC38580 |
Le RU-301 est un inhibiteur pan-TAM qui bloque l'activation et la tumorigénicité induites par Gas6 TAM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1110873-99-8
Sample solution is provided at 25 µL, 10mM.
RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively[1].
[1]. Kimani SG, et al. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Sci Rep. 2017 Mar 8;7:43908.
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