Melittin (C-Term Cysteine labeled) (trifluoroacetate salt)

Melittin (C-term cysteine labeled) is a derivative of the cytotoxic bee venom peptide melittin with a cysteine residue at the C-terminus.^1,2 It induces hemolysis of isolated human red blood cells at endosomal and extracellular pHs (EC₅₀s = 5 and 6 µM at pH 5.5 and 7.4, respectively).¹ Melittin (C-term cysteine labeled) has been used in the synthesis of membrane-lytic polymers that have been used in the generation of polyplexes for plasmid delivery in vitro and in vivo.²