Onc112 acetate is a proline-rich antimicrobial peptide that displays potent activity against Gram-negative bacteria. Onc112 acetate inhibits translation by blocking and destabilizing the initiation complex [1].
References:
[1]. Seefeldt AC, et al. The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex. Nat Struct Mol Biol. 2015 Jun;22(6):470-5.
References:
[1]. Seefeldt AC, et al. The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex. Nat Struct Mol Biol. 2015 Jun;22(6):470-5.