PFM 01 |
| Catalog No.GC50388 |
Le PFM 01, dérivé N-alkylé de Mirin, est un inhibiteur de l'endonucléase MRE11. Le PFM 01 peut réguler la réparation des cassures double brin (DSBR) par jonction d'extrémité non homologue (NHEJ) par rapport à la recombinaison homologue (HR).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1558598-41-6
Sample solution is provided at 25 µL, 10mM.
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MRE11 endonuclease inhibitor. Prevents double-stranded break (DSB) resection. Enhances non-homologous end-joining (NHEJ) and reduces homologous recombination.
Shibata et al (2014) DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Mol.Cell 53 7 PMID:24316220
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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