(Rac)-CP-601927 hydrochloride |
| Catalog No.GC63511 |
Le chlorhydrate de (Rac)-CP-601927 est le racémate du CP-601927.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 230615-01-7
Sample solution is provided at 25 µL, 10mM.
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(Rac)-CP-601927 hydrochloride is the racemate of CP-601927. CP-601927 is a nAChR agonist with Ki values 1.2 nM and 102 nM for α4β2 and α3β4 nAChR, respectively[1].
CP-601927 induces significant antidepressant-like effects in mice. CP-601927 could decrease cholinergic signaling as a result of its reduced efficacy or via desensitization of α4β2* nAChRs[1].
[1]. Yann S Mineur, et al. α4β2 nicotinic acetylcholine receptor partial agonists with low intrinsic efficacy have antidepressant-like properties. Behav Pharmacol. 2011 Aug;22(4):291-9.
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