Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Products Related to Drug Metabolite(546)
- GC49399N-Desbutyl Dronedarone (hydrochloride)CAS: 197431-02-0Purity: >95.00%
Le chlorhydrate de débutyldronédarone (SR35021), principal métabolite de la dronédarone, est un inhibiteur sélectif du récepteur de l'hormone thyroÏdienne α1 (TRα1).
- GC49406ACT-373898CAS: 1433875-14-9Purity: >90.00%
ACT-373898 est un métabolite acide carboxylique inactif du macitentan.
- GC49421Atorvastatin lactone-d5CAS: 125995-03-1Purity: >99.00%
An internal standard for the quantification of atorvastatin lactone
- GC49428O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipineCAS: 113994-45-9Purity: >95.00%
A major metabolite of amlodipine
- GC49480Salicylic Acid-d4CAS: 78646-17-0Purity: >98.00%
L'acide salicylique-d4 est le 2-carboxyphénol marqué au deutérium.
- GC494886-Methylmercaptopurine-d3CAS: 33312-93-5Purity: >99.00%
An internal standard for the quantification of 6-MMP
- GC49559Hydroxymethyl Tolperisone (hydrochloride)CAS: 352233-14-8Purity: >95.00%
A metabolite of tolperisone
- GC49565RoxatidineCAS: 78273-80-0Purity: >95.00%
La roxatidine est un métabolite actif du chlorhydrate d'acétate de roxatidine, est un antagoniste des récepteurs H2 de l'histamine.
- GC49583N-desmethyl Sertraline (hydrochloride)CAS: 675126-09-7Purity: >95.00%
A metabolite of sertraline
- GC49637O-desethyl DapagliflozinCAS: 864070-37-1Purity: >98.00%
An SGLT2 inhibitor and active metabolite of dapagliflozin
- GC49677Olmesartan-d6CAS: 1185144-74-4Purity: >99.00%
An internal standard for the quantification of olmesartan
- GC49686N-desmethyl Regorafenib N-oxideCAS: 835621-12-0Purity: >90.00%
An active metabolite of regorafenib
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49399 | N-Desbutyl Dronedarone (hydrochloride) | 197431-02-0 | >95.00% | |
Le chlorhydrate de débutyldronédarone (SR35021), principal métabolite de la dronédarone, est un inhibiteur sélectif du récepteur de l'hormone thyroÏdienne α1 (TRα1). | ||||
| GC49403 | Benzarone | 1477-19-6 | >98.00% | |
Benzarone (Fragivix) est un puissant inhibiteur du transporteur 1 de l'acide urique humain (hURAT1), avec une IC50 de 2,8 μM dans l'ovocyte. | ||||
| GC49406 | ACT-373898 | 1433875-14-9 | >90.00% | |
ACT-373898 est un métabolite acide carboxylique inactif du macitentan. | ||||
| GC49409 | Desmethyl Ranolazine | 172430-45-4 | >95.00% | |
A metabolite of ranolazine | ||||
| GC49410 | CVT-2738 | 5294-61-1 | >98.00% | |
An active metabolite of ranolazine | ||||
| GC49421 | Atorvastatin lactone-d5 | 125995-03-1 | >99.00% | |
An internal standard for the quantification of atorvastatin lactone | ||||
| GC49428 | O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine | 113994-45-9 | >95.00% | |
A major metabolite of amlodipine | ||||
| GC49480 | Salicylic Acid-d4 | 78646-17-0 | >98.00% | |
L'acide salicylique-d4 est le 2-carboxyphénol marqué au deutérium. | ||||
| GC49488 | 6-Methylmercaptopurine-d3 | 33312-93-5 | >99.00% | |
An internal standard for the quantification of 6-MMP | ||||
| GC49501 | Nirvanol | 631-07-2 | >98.00% | |
An active metabolite of mephenytoin | ||||
| GC49511 | Nicorandil N-oxide | 107833-98-7 | >98.00% | |
A metabolite of nicorandil | ||||
| GC49538 | Lamotrigine N2-oxide | 136565-76-9 | >95.00% | |
A metabolite of lamotrigine | ||||
| GC49544 | 8-hydroxy Mirtazapine | 102335-57-9 | >95.00% | |
A metabolite of mirtazapine | ||||
| GC49559 | Hydroxymethyl Tolperisone (hydrochloride) | 352233-14-8 | >95.00% | |
A metabolite of tolperisone | ||||
| GC49565 | Roxatidine | 78273-80-0 | >95.00% | |
La roxatidine est un métabolite actif du chlorhydrate d'acétate de roxatidine, est un antagoniste des récepteurs H2 de l'histamine. | ||||
| GC49575 | 4-hydroxy Omeprazole sulfide | 103876-98-8 | >98.00% | |
A metabolite of omeprazole | ||||
| GC49583 | N-desmethyl Sertraline (hydrochloride) | 675126-09-7 | >95.00% | |
A metabolite of sertraline | ||||
| GC49627 | Rabeprazole sulfone | 117976-47-3 | >95.00% | |
A metabolite of rabeprazole | ||||
| GC49629 | 6β-hydroxy Prednisolone | 16355-29-6 | >95.00% | |
A metabolite of prednisolone | ||||
| GC49637 | O-desethyl Dapagliflozin | 864070-37-1 | >98.00% | |
An SGLT2 inhibitor and active metabolite of dapagliflozin | ||||
| GC49655 | 5-hydroxy Buspirone | 105496-33-1 | >95.00% | |
A metabolite of buspirone | ||||
| GC49676 | 6β-hydroxy Budesonide | - | >95.00% | |
A metabolite of budesonide | ||||
| GC49677 | Olmesartan-d6 | 1185144-74-4 | >99.00% | |
An internal standard for the quantification of olmesartan | ||||
| GC49686 | N-desmethyl Regorafenib N-oxide | 835621-12-0 | >90.00% | |
An active metabolite of regorafenib | ||||