SSTC3 |
| Catalog No.GC39637 |
SSTC3 est un activateur de la caséine kinase 1α (CK1α) (Kd = 32 nM) qui inhibe la signalisation WNT (EC50 = 30 nM). SSTC3 présente une toxicité gastro-intestinale minimale par rapport aux autres classes d'inhibiteurs de WNT.
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Cas No.: 1242422-09-8
Sample solution is provided at 25 µL, 10mM.
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SSTC3 is a casein kinase 1α (CK1α) activator (Kd = 32 nM) that inhibits WNT signaling (EC50 = 30 nM). SSTC3 exhibits minimal gastrointestinal toxicity compared to other classes of WNT inhibitors[1].
[1]. Li B, et al, Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors. Sci Signal. 2017 Jun 27;10(485). pii: eaak9916.
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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