TY-51469 |
| Catalog No.GC32004 |
Le TY-51469 est un inhibiteur de la chymase avec des IC50 pour les chymases simiennes et humaines de 0,4 et 7,0 nM, respectivement.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 603987-59-3
Sample solution is provided at 25 µL, 10mM.
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TY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively.
TY-51469 shows 100% stability in rat plasma at 40°C for as long as 1 hour[1]. TY-51469 suppresses the accumulation of neutrophils in the lung and reduces silica-induced pulmonary fibrosis in mice[2].
[1]. Takato H, et al. The specific chymase inhibitor TY-51469 suppresses the accumulation of neutrophils in the lung and reduces silica-induced pulmonary fibrosis in mice. Expert Opinion on Therapeutic Targets Volume 15, 2011 - Issue 4.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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