U-74389G (Synonyms: Methylated Tirilazad) |
| Catalog No.GC45108 |
U-74389G (méléate de PNU74389G) est un antioxydant, peut inhiber les réactions de peroxydation lipidique.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 153190-29-5
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It protects against ischemia-reperfusion injury in animal heart, liver, and kidney models.[1],[2],[3],[4]
Reference:
[1]. Ishizaki, N., Zhu, Y., Zhang, S., et al. Comparison of various lazaroid compounds for protection against ischemic liver injury. Transplantation 63, 202-208 (1997).
[2]. Palma-Vargas, J.M., Toledo, A.H., García-Criado, F.J., et al. 21-Aminosteroids block neutrophil infiltration and provide liver protection independent of nitrite/nitrate levels. Journal of Surgical Research 66, 131-137 (1996).
[3]. Perna, A.M., Liguori, P., Bonacchi, M., et al. Protection of rat heart from ischaemia-reperfusion injury by the 21-aminosteroid U-74389G. Pharmacological Research 34, 25-31 (1996).
[4]. Shoskes, D.A., Xie, Y., and Gonzalez-Cadavid, N.F. Nitric oxide synthase activity in renal ischemia-reperfusion injury in the rat. Implications for renal transplantation. Transplantation 63, 495-500 (1997).
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *