Vezocolmitide (ST-100) is a collagen mimetic peptide. Vezocolmitide can rapidly repair damaged collagen triple helix structures, thereby quickly reversing damage to the ocular surface and extracellular matrix, and restoring corneal nerve function while repairing the epithelium. Vezocolmitide can be used for research of dry eye disease (DED) [1].
In Vitro, Vezocolmitide improves tear production, alleviates ocular surface damage, and relieves discomfort in dry eye disease, with a favorable safety and tolerability profile[1].
References:
[1]. Baratta RO, et al., A Phase 2 Trial to Test Safety and Efficacy of ST-100, a Unique Collagen Mimetic Peptide Ophthalmic Solution for Dry Eye Disease. Ophthalmol Sci. 2023 Dec 12;4(3):100451.
In Vitro, Vezocolmitide improves tear production, alleviates ocular surface damage, and relieves discomfort in dry eye disease, with a favorable safety and tolerability profile[1].
References:
[1]. Baratta RO, et al., A Phase 2 Trial to Test Safety and Efficacy of ST-100, a Unique Collagen Mimetic Peptide Ophthalmic Solution for Dry Eye Disease. Ophthalmol Sci. 2023 Dec 12;4(3):100451.