GLPBio

FR901379

Catalog No.: GC46149Purity:>90.00%
COASDSData Sheet
An antifungal lipopeptide

Products are for research use only. Not for human use. We do not sell to patients.

FR901379
Cas No.: 144371-88-0
1mgIn Stock
$149.00
1
5mgIn Stock
$554.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    641, 529–536 (2025)
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    628, 630–638 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

FR901379 is an echinocandin-like antifungal lipopeptide.1 It is active against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR901379 is protective against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of pulmonary cysts and trophozoites in a mouse model of P. carinii infection.

|1. Fujie, A., Iwamoto, T., Sato, B., et al. FR131535, a novel water-soluble echinocandin-like lipopeptide: Synthesis and biological properties. Bioorg. Med. Chem. Lett. 11(3), 399-402 (2001).

Product Documents

Purity:>90.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
144371-88-0
SMILES
O=C(N[C@]([C@H](O)CC(N)=O)([H])C(N1[C@@](C(N[C@H](O)[C@H](O)C[C@@H]2NC(CCCCCCCCCCCCCCC)=O)=O)([H])[C@@H](O)[C@@H](C)C1)=O)[C@@]([C@H](O)[C@@H](O)C3=CC=C(O)C(OS(O)(=O)=O)=C3)([H])NC([C@@]4([H])N(C([C@@]([C@H](O)C)([H])NC2=O)=O)C[C@H](O)C4)=O
Molecular Formula
C51H82N8O21S
Molecular Weight
1175.3
Solubility
Methanol: slightly soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

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