GLPBio

(Pen⁵)-Urotensin II (4-11) (human)

Catalog No.: GA20269Purity:>98%
(Pen?)-Urotensin II (4-11) (human) (P5U) is the most potent urotensin-II receptor agonist reported to date. It has been shown to exhibit a 3-fold higher affinity for the receptor (measured in competition experiments) than urotensin-II (human) (H-4768). P5U might represent a useful tool for the study of the human urotensin-II/orphan G-protein-coupled receptor GPR14 system.

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(Pen⁵)-Urotensin II (4-11) (human)
Cas No.: 473902-31-7
1mgIn Stock
$1,030.00
1
5mgIn Stock
$3,821.00
1

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

(Pen5)-Urotensin II (4-11) (human) (P5U) is the most potent urotensin-II receptor agonist reported to date. It has been shown to exhibit a 3-fold higher affinity for the receptor (measured in competition experiments) than urotensin-II (human). P5U migh

Chemical Properties

CAS No.
473902-31-7
Molecular Formula
C52H68N10O12S2
Molecular Weight
1089.3
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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