Boc-Arg-Val-Arg-Arg-AMC |
| Catalog No.GA20901 |
The fluorogenic substrate Boc-RVRR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 4.10³ M?¹s?¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is responsible for the secretory processing of precursor proteins at paired basic residues. Boc-RVRR-AMC is also cleaved by proprotein convertase 4. Stock solutions of Boc-RVRR-AMC are best prepared in DMSO.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 136132-77-9
Sample solution is provided at 25 µL, 10mM.
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The fluorogenic substrate Boc-RVRR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 4.10³ M¹s¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is re
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