GLPBio

Collagen Type IV α3 Chain (185-203)

Catalog No.: GA21277Purity:>98%
The collagen IV fragment CNYYSNSYSFWLASLNPER inhibits the activation of polymorphonuclear leukocytes. It promotes adhesion of human melanoma cells and inhibits their proliferation by 40%. These properties appear to be dependent on the presence of the triplet sequence -Ser-Asn-Ser- (residues 189-191), which is unique in the α3 chain and may represent an important functional epitope.

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Collagen Type IV α3 Chain (185-203)
Cas No.: 157802-35-2
0.5mgIn Stock
$672.00
1
1mgIn Stock
$1,131.00
1

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

The collagen IV fragment CNYYSNSYSFWLASLNPER inhibits the activation of polymorphonuclear leukocytes. It promotes adhesion of human melanoma cells and inhibits their proliferation by 40%. These properties appear to be dependent on the presence of the t

Chemical Properties

CAS No.
157802-35-2
Molecular Formula
C105H144N26O32S
Molecular Weight
2314.52
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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