H-Gly-Pro-Gly-Gly-OH is a characteristic tetrapeptide composed of a glycine-proline-glycine-glycine sequence[1]. H-Gly-Pro-Gly-Gly-OH can be used as an important molecular building block in research for the synthesis of more complex polypeptides. H-Gly-Pro-Gly-Gly-OH also provides a concise model sequence for investigating protein-protein interactions, particularly those involved in cell adhesion and signal transduction[2].
References:
[1] Harrison A G, Young A B. Fragmentation reactions of deprotonated peptides containing proline. The proline effect[J]. Journal of mass spectrometry, 2005, 40(9): 1173-1186.
[2] Richard T, Vergé S, Berké B, et al. NMR and simulated annealing investigations of bradykinin in presence of polyphenols[J]. Journal of Biomolecular Structure and Dynamics, 2001, 18(4): 627-637.