Selective somatostatin receptor subtype sst4 agonist. In competitive radioligand displacement experiments using the non-selective radioligand ([¹²I]-(Leu,D-Trp²²,Tyr²)-Somatostatin-28, YCFAWKTFC exhibited a high affinity for ss
H-Tyr-Cys-Phe-Ala-Trp-Lys-Thr-Phe-Cys-OH
Catalog No.: GA22966Purity:>98.00%
Selective somatostatin receptor subtype sst4 agonist. In competitive radioligand displacement experiments using the non-selective radioligand ([¹²?I]-(Leu?,D-Trp²²,Tyr²?)-Somatostatin-28, YCFAWKTFC exhibited a high affinity for sst4 with an IC?? value of 2.0 ± 0.5 nM. IC?? values for sst1, sst2, sst3, and sst5 were >1000 nM, 622 ± 85 nM, 624 ± 213 nM, and 692 ± 166 nM, respectively. The nonapeptide YCFAWKTFC may serve as a lead compound or tool for preclinical and clinical studies.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 647016-22-6
1mgIn Stock
$315.00
1
5mgIn Stock
$958.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $315.00 | In Stock | 1 | |
| 5mg | $958.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
647016-22-6
Molecular Formula
C57H71N11O12S2
Molecular Weight
1166.39
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
Reviews
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