SPLUNC1 is an endogenous inhibitor of the epithelial sodium channel (ENaC) which is responsible for Na and fluid absorption across colon, kidney, and airway epithelia. The partial sequence GGLPVPLDQTLPLNVNPA (SPLUNC1 22-39) corresponds to the ENaC inhi
SPLUNC1 (22-39)
Catalog No.: GA23513Purity:>98%
SPLUNC1 is an endogenous inhibitor of the epithelial sodium channel (ENaC) which is responsible for Na? and fluid absorption across colon, kidney, and airway epithelia. The partial sequence GGLPVPLDQTLPLNVNPA (SPLUNC1 22-39) corresponds to the ENaC inhibitory domain of SPLUNC1. As ENaC hyperactivity contributes to the development of cystic fibrosis in the lungs, the fragment could help to develop new strategies for the treatment of this genetic disorder.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1421132-47-9
0.5mgIn Stock
$275.00
1
1mgIn Stock
$392.00
1
5mgIn Stock
$1,267.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 0.5mg | $275.00 | In Stock | 1 | |
| 1mg | $392.00 | In Stock | 1 | |
| 5mg | $1,267.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Chemical Properties
CAS No.
1421132-47-9
Molecular Formula
C82H135N21O25
Molecular Weight
1815.1
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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