GLPBio

Z-Leu-Leu-Tyr-α-keto aldehyde

Catalog No.: GA23855Purity:>98.00%
Z-LLY-α-keto aldehyde (peptidyl glyoxal), previously shown to be an excellent inhibitor of the serine and cysteine proteases, was found to be an excellent inhibitor of the chymotryptic-like activity of proteasome exhibiting a Ki value of approximately 3.0 nM. Such inhibitor might be valuable in the characterization of the role of proteasome in normal and aberrant pathways of protein catabolism in the cell.

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Z-Leu-Leu-Tyr-α-keto aldehyde
Cas No.: 204649-66-1
5mgIn Stock
$744.00
1
25mgIn Stock
$2,675.00
1

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Z-LLY-α-keto aldehyde (peptidyl glyoxal), previously shown to be an excellent inhibitor of the serine and cysteine proteases, was found to be an excellent inhibitor of the chymotryptic-like activity of proteasome exhibiting a Ki value of approxima

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
204649-66-1
Molecular Formula
C30H39N3O7
Molecular Weight
553.66
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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