GLPBio

GAPDH Inhibitor Compound F8

Catalog No.: GC91975Purity:>95.00%
COASDSData Sheet

GAPDH inhibitor compound F8 is a covalent inhibitor of GAPDH (IC50 = 39.31 μM).

Products are for research use only. Not for human use. We do not sell to patients.

GAPDH Inhibitor Compound F8
Cas No.: 252212-58-1
1 mgIn Stock
$49.00
1
5 mgIn Stock
$221.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    31, 1291–1307 (2021)

Description

GAPDH inhibitor compound F8 is a covalent inhibitor of GAPDH (IC50 = 39.31 μM).1 It viability of, and glucose metabolism in, HEK293 cells in a concentration-dependent manner.

References:
[1]. Jung, Y., Noda, N., Takaya, J., et al.Discovery of non-cysteine-targeting covalent inhibitors by activity-based proteomic screening with a cysteine-reactive probeACS Chem. Biol.17(2)340-347(2022).

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
252212-58-1
Chemical Name
2,5-bis[3-(2-oxiranylmethoxy)phenyl]-1,3,4-oxadiazole
SMILES
C1(C2=CC(OCC3OC3)=CC=C2)=NN=C(C4=CC=CC(OCC5CO5)=C4)O1
Molecular Formula
C20H18N2O5
Molecular Weight
366.4
Solubility
Acetonitrile: Slightly soluble: 0.1-1 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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