(±)-Menthyl acetate is a menthol acyl derivative (monoterpene ester) and antibacterial agent found in the essential oil of Mentha arvensis L.. (±)-Menthyl acetate inhibits growth of Gram-positive bacterial strains including Streptococcus mutans, Mycobacterium smegmatis, Enterococcus faecalis, Staphylococcus aureus, and Bacillus subtilis. (±)-Menthyl acetate is inactive against tested fungal strains. (±)-Menthyl acetate can be used in the research of Gram-positive bacterial infections [1].
In Vitro, Menthyl acetate (Compound 19) (50 μg/disc; 48 h) inhibits the growth of Gram-positive bacterial strains Streptococcus mutans, Mycobacterium smegmatis, Enterococcus faecalis, Staphylococcus aureus, and Bacillus subtilis, with the largest net inhibition zone (15 mm) against Bacillus subtilis, and shows no activity against tested Gram-negative bacterial strains[1]. Menthyl acetate (50 μg/disc; 3-10 days) shows no antifungal activity against tested fungal strains[1].
References:
[1]. Kumar, A., Singh, S. P., & Chhokar, S. S. (2011). Antimicrobial activity of the major isolates of mentha oil and derivatives of menthol. Analytical Chemistry Letters, 1(1), 70-85.
In Vitro, Menthyl acetate (Compound 19) (50 μg/disc; 48 h) inhibits the growth of Gram-positive bacterial strains Streptococcus mutans, Mycobacterium smegmatis, Enterococcus faecalis, Staphylococcus aureus, and Bacillus subtilis, with the largest net inhibition zone (15 mm) against Bacillus subtilis, and shows no activity against tested Gram-negative bacterial strains[1]. Menthyl acetate (50 μg/disc; 3-10 days) shows no antifungal activity against tested fungal strains[1].
References:
[1]. Kumar, A., Singh, S. P., & Chhokar, S. S. (2011). Antimicrobial activity of the major isolates of mentha oil and derivatives of menthol. Analytical Chemistry Letters, 1(1), 70-85.