(3-Aminopropyl)dimethylmethoxysilane |
Catalog No.GD01758
One-Click Copy Product Info
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(3-aminopropyl)dimethylmethoxysilane (APDMS) is a silane compound containing an amino group. It is a commonly used surface-modifying reagent and is widely applied in the surface modification of silicon-based materials. The amino group in (3-aminopropyl)dimethylmethoxysilane endows (3-aminopropyl)dimethylmethoxysilane with high reactivity, especially in reactions with silicon-based materials (such as silica), where it exhibits unique catalytic properties.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 31024-26-7
Sample solution is provided at 25 µL, 10mM.
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(3-aminopropyl)dimethylmethoxysilane (APDMS) is a silane compound containing an amino group. It is a commonly used surface-modifying reagent and is widely applied in the surface modification of silicon-based materials. The amino group in (3-aminopropyl)dimethylmethoxysilane endows (3-aminopropyl)dimethylmethoxysilane with high reactivity, especially in reactions with silicon-based materials (such as silica), where it exhibits unique catalytic properties.
References:
[1] Frei R, Blitz JP, Gun'ko VM, Frost BE, Sergeev VS. Kinetics and computational studies of an aminosilane reaction with a silsesquioxane silanol. J Phys Chem A. 2009 Jun 18;113(24):6612-9.
Hydrogel synthesis[1]
This protocol only provides a guideline, and should be modified according to your specific needs.
1、Hydrogels cross-linked with (3-aminopropyl)dimethylmethoxysilane were prepared by blending natural polymers (k-carrageenan (k-CG) and sodium alginate (SA)) with a synthetic polymer (polyvinyl alcohol (PVA)) (MW: 65000g/mol) using the solution casting technique.
2、Initially, k-CG (0.25g) and SA (0.25g) were each dissolved in 30mL of distilled water. The two solutions were then mixed and stirred for 1h.
3、Subsequently, PVA (0.5g) was dissolved in 30mL of distilled water and transferred to the aforementioned polymeric solution, where it was blended for 1.5h.
4、In the next step, Polyamidoamine Dendrimers (PAA) (60µL) was diluted in 3mL of methanol and added to the mixture, followed by stirring for over 1h. Thereafter, different amounts of (3-aminopropyl)dimethylmethoxysilane (80, 160, 240 and 320µL) were each diluted in 5mL of ethanol and added to the mixture.
5、After stirring at 70°C for 3h, the mixture was poured into Petri dishes and dried at room temperature.
6、The hydrogels were named CAP (control), CAP-8, CAP-16, CAP-24, and CAP-32. CAP (control) contained no (3-aminopropyl)dimethylmethoxysilane, while CAP-8, CAP-16, CAP-24, and CAP-32 contained 80, 160, 240 and 320µL of (3-aminopropyl)dimethylmethoxysilane cross-linker, respectively. The entire hydrogel fabrication process was completed at 70°C with continuous stirring.
References:
[1] Anees Ur Rehman Qureshi M, Arshad N, Rasool A, Janjua NK, Butt MS, Naqeeb Ur Rehman Qureshi M, Ismail H. Kappa-carrageenan and sodium alginate-based pH-responsive hydrogels for controlled release of methotrexate. R Soc Open Sci. 2024 Apr 24;11(4):231952.
| Cas No. | 31024-26-7 | SDF | |
| Formula | C6H17NOSi | M.Wt | 147.29 |
| Solubility | Storage | Store at room temperature | |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 6.7893 mL | 33.9466 mL | 67.8933 mL |
| 5 mM | 1.3579 mL | 6.7893 mL | 13.5787 mL |
| 10 mM | 678.9 μL | 3.3947 mL | 6.7893 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >95.00% Appearance: A liquid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)