2, 4-D sodium salt (25-200 渭M, 72 h) inhibits the cell viability of A549 and WI38 with IC50 values of 126 卤 2.25碌M and 115 卤 4.39碌M, respectively. By influencing cell cycle, apoptosis was induced[2].
2,4-D sodium salt (100 or 200 mg/kg, gavage for 30 days) has toxic effects on the reproductive system of male rats[3].
[1]. Germaine KJ, et al. Bacterial endophyte-enhanced phytoremediation of the organochlorine herbicide 2,4-dichlorophenoxyacetic acid. FEMS Microbiol Ecol. 2006 Aug;57(2):302-10.
[2]. Ganguli A, et al. 2, 4-Dichlorophenoxyacetic acid induced toxicity in lung cells by disruption of the tubulin-microtubule network. Toxicology Research, 2014, 3(2): 118-130.
[3]. Marouani N, et al. Effects of oral administration of 2,4-dichlorophenoxyacetic acid (2,4-D) on reproductive parameters in male Wistar rats. Environ Sci Pollut Res Int. 2017 Jan;24(1):519-526.
















