GLPBio

Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c]pyridine-3-carboxylate

Catalog No.: GD12636Purity:>95.00%
COASDSData Sheet

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Ethyl 2-amino-6-benzyl-4,5,6,7-tetrahydrothieno [2,3-c]pyridine-3-carboxylate
Cas No.: 24237-54-5
1gIn Stock
$62.00
1
5gIn Stock
$197.00
1
25gIn Stock
$549.00
1
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Citations

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Tinoridine (Y-3642) is an orally active non-steroidal anti-inflammatory agent with potent antiperoxidative ability and radical scavenger activity. Tinoridine acts function by inhibiting COX enzyme, involves in hepatotoxicity inhibition. .

Tinoridine (10-100 渭M) exerts effect on stability of rat liver and kidney lysosomes, and liver parenchymal cells[3].
Tinoridine (1, 10, and 100 渭M; 30 min) inhibits spontaneous release of acid phosphatase from liver lymomoses in vitro[3].

Tinoridine (100 mg/kg; p.o.; single dose) inhibits CCl4 hepatotoxicity in rats, with a strong control of the CCl4-induced enzyme activities[2].
Tinoridine (100 mg/kg; i.p.; single dose) protects the stability of rat liver and kidney lysosomes in vivo[3].

[1]. da Cruz RMD, et al. Thiophene-Based Compounds with Potential Anti-Inflammatory Activity. Pharmaceuticals (Basel). 2021 Jul 19;14(7):692.  

[2]. Yasuda H, et al. The protective effect of tinoridine against carbon tetrachloride hepatotoxicity. Toxicol Appl Pharmacol. 1980 Mar 15;52(3):407-13.  

[3]. Goto K, et al. Effect of tinoridine on stability of rat liver and kidney lysosomes, and liver parenchymal cells. Biochem Pharmacol. 1977 Jan 1;26(1):11-8.  

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
24237-54-5
Solubility
DMSO : 125 mg/mL (395.04 mM; Need ultrasonic)
Storage
Store at room temperature
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion

g/mol

Reviews

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