GLPBio

((2R,7As)-2-fluorohexahydro-1H-pyrrolizin-7a-yl)methanol

Catalog No.: GD13882Purity:>99.00%
(2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizine-7a(5H)-methanol is adrug intermediatefor synthesis of various active compounds.

Products are for research use only. Not for human use. We do not sell to patients.

((2R,7As)-2-fluorohexahydro-1H-pyrrolizin-7a-yl)methanol
Cas No.: 2097518-76-6
500mgIn Stock
$10.00
1
1gIn Stock
$18.00
1
5gIn Stock
$61.00
1
10gIn Stock
$104.00
1
25gIn Stock
$219.00
1
50gIn Stock
$373.00
1
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Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

(2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizine-7a(5H)-methanol is adrug intermediatefor synthesis of various active compounds. (2R,7aS)-2-Fluorotetrahydro-1H-pyrrolizine-7a(5H)-methanol is a core structural framework of the compounds targeting KRAS G12D mutation.

References:
[1].Preparation method for ((2r,7as)-2-fluorohexahydro-1h-pyrrolizin-7a-yl)methanol. WO2024092420A1

Product Documents

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Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
2097518-76-6
Molecular Formula
C8H14FNO
Molecular Weight
159.2
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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