IITR01324 is an antimicrobial agent. IITR01324 has antimicrobial activity againstEscherichia coli(MIC = 3.58 mg/L) andotherGram-negative bacteria (Shigella flexneri: MIC = 3.58 mg/L;Cronobacter sakazakii: MIC = 28.63 mg/L). IITR01324 exerts its antimicrobial activity by destroyingbacterialDNA after activation of intracellular reductases. IITR01324 can be used to study the development of new antimicrobial drugs, especially against multidrug-resistant (MDR) pathogens[1].
References:
[1].Bhando T,et al. Antibacterial properties and in vivo efficacy of a novel nitrofuran, IITR06144, against MDR pathogens. J Antimicrob Chemother. 2020 Feb 1;75(2):418-428.