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Regaloside A

Catalog No.GD20805 Copy One-Click Copy Product Info

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Regaloside A Chemical Structure

Cas No.: 114420-66-5

Size Price Stock Qty
5mg
$113.00
In stock
10mg
$189.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of Regaloside A

Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity.

Regaloside A (50 渭g/mL; 2 hours) inhibits the expression of iNOS to 70.3 decreasing COX-2 expression to 131.6 in Raw 264.7 cells treated with LPS (1 渭g/ml; pretreatment for 15 min). Regaloside A decreases the ratio of p-p65/p-65 to 40.7[1].
Regaloside A (50 渭g/mL; pretreatment for 2 hours) decreases the expression of VCAM-1 to 48.6 in HASMCs with TNF-a (10 ng/ml; for 12 h)[1].

[1]. Nhan Nguyen Thi, et al. Phenylpropanoids from Lilium Asiatic hybrid flowers and their anti-inflammatory activities. Appl Biol Chem (2017) 60(5):527鈥?33.

Chemical Properties of Regaloside A

Cas No. 114420-66-5 SDF
Formula C18H24O10 M.Wt 400.38
Solubility DMSO : 100 mg/mL (249.76 mM; Need ultrasonic) Storage 2-8°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Regaloside A

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.4976 mL 12.4881 mL 24.9763 mL
5 mM 499.5 μL 2.4976 mL 4.9953 mL
10 mM 249.8 μL 1.2488 mL 2.4976 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Regaloside A

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for Regaloside A

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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