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1,1,2,2-Tetrafluoroethyl methyl ether

Catalog No.GD21958 Copy One-Click Copy Product Info

1,1,2,2-Tetrafluoroethyl methyl ether is a fluoromethyl ether compound, a colorless, transparent liquid, used as a special solvent in organic synthesis, especially suitable for reactions that require an inert environment (such as fluorine chemical transformations), and has good solubility for some polar and non-polar organic compounds.

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1,1,2,2-Tetrafluoroethyl methyl ether Chemical Structure

Cas No.: 425-88-7

Size Price Stock Qty
25g
$31.00
In stock
100g
$93.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of 1,1,2,2-Tetrafluoroethyl methyl ether

1,1,2,2-Tetrafluoroethyl methyl ether is a fluoromethyl ether compound, a colorless, transparent liquid, used as a special solvent in organic synthesis, especially suitable for reactions that require an inert environment (such as fluorine chemical transformations), and has good solubility for some polar and non-polar organic compounds[1, 2]. 1,1,2,2-Tetrafluoroethyl methyl ether can be used as a co-solvent for lithium-ion batteries[3, 4].

References:
[1] Zhao X, Fu Z, Zhang X, et al. More is better: high-entropy electrolyte design in rechargeable batteries[J]. Energy & Environmental Science, 2024, 17(7): 2406-2430.
[2] Leroux F, Jeschke P, Schlosser M. α-Fluorinated ethers, thioethers, and amines: anomerically biased species[J]. Chemical reviews, 2005, 105(3): 827-856.
[3] Wang R. Synthesis and application of a highly fluorinated ether molecule as an electrolyte co-solvent for enhanced performance rechargeable lithium batteries[D]. University of Birmingham, 2024.
[4] Ouyang D, Liu B, Wan X, et al. An all-fluorinated electrolyte with 1, 1, 2, 2-tetrafluoroethyl-2, 2, 3, 3-tetrafluoropropylether as co-solvent for lithium-ion cells with advanced electrochemical and safety properties at high voltage[J]. Journal of Power Sources, 2024, 615: 235095.

Chemical Properties of 1,1,2,2-Tetrafluoroethyl methyl ether

Cas No. 425-88-7 SDF
Formula CH3OCF2CHF2 M.Wt 132.06
Solubility Storage 2-8°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of 1,1,2,2-Tetrafluoroethyl methyl ether

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 7.5723 mL 37.8616 mL 75.7232 mL
5 mM 1.5145 mL 7.5723 mL 15.1446 mL
10 mM 757.2 μL 3.7862 mL 7.5723 mL
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In vivo Formulation Calculator (Clear solution) of 1,1,2,2-Tetrafluoroethyl methyl ether

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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