GLPBio

LASV inhibitor 3.3

Catalog No.: GF10366Purity:>98.00%Synonyms: LASV inhibitor 3.3

Products are for research use only. Not for human use. We do not sell to patients.


LASV inhibitor 3.3
Cas No.: 554438-52-7
10mgIn Stock
$158.00
1

Citations

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    641, 529–536 (2025)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    35, 97–116 (2025)
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Description

LASV inhibitor 3.3 is a Lassa fever virus (LASV) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research.

LASV inhibitor 3.3 (1 nM-100 渭M; 1 h) inhibits transduction by murine leukemia virus (MLV) pseudotyped with the indicated viral glycoproteins with an IC50 value of 1.8 渭M[1].
LASV inhibitor 3.3 (1 and 10 渭M; 1 h) inhibits LAMP1 binding to LASV GP in vitro[1].

[1]. Wang MK, et al. Critical role for cholesterol in Lassa fever virus entry identified by a novel small molecule inhibitor targeting the viral receptor LAMP1. PLoS Pathog. 2018 Sep 28;14(9):e1007322.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
554438-52-7
Synonyms
LASV inhibitor 3.3
Molecular Formula
C30H37N3O2
Molecular Weight
471.645
Solubility
DMSO : 25 mg/mL (53.01 mM; Need ultrasonic)
Storage
-20°C, sealed storage,away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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