GLPBio

GS-441285 1′-cyano-2′-C-methyl-4-aza-7，9-dideazaadenosine

Catalog No.: GF11093Synonyms: 1'-Cyano-2'-C-methyl 4-aza-7,9-dideaza adenosine
COASDSData Sheet
GS-6620 PM (Compound 2) is an analog of 2′-C-methyl 4-aza-7,9-dideaza adenosine.

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GS-441285 1′-cyano-2′-C-methyl-4-aza-7，9-dideazaadenosine
Cas No.: 1191237-49-6
10mgIn Stock
$2,574.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

GS-6620 PM (Compound 2) is an analog of 2′-C-methyl 4-aza-7,9-dideaza adenosine. 2′-C-methyl 4-aza-7,9-dideaza adenosine is an inhibitor ofHCVreplication incell culture. GS-6620 PM can be used in the study of hepatitis C virus (HCV)infection[1].

References:
[1].Cho A, et al. Discovery of the first C-nucleoside HCV polymerase inhibitor (GS-6620) with demonstrated antiviral response in HCV infected patients. J Med Chem. 2014 Mar 13;57(5):1812-25.

Product Documents

Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1191237-49-6
Synonyms
1'-Cyano-2'-C-methyl 4-aza-7,9-dideaza adenosine
Molecular Formula
C13H15N5O4
Molecular Weight
305.29
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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