GLPBio

AC-263093

Catalog No.: GF17153Purity:>98.00%Synonyms: AC-263093

Products are for research use only. Not for human use. We do not sell to patients.


AC-263093
Cas No.: 849459-86-5
10mgIn Stock
$2,516.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

AC-263093 (AC-093) functionally activates NPFFR2 and blocks activation of NPFFR1 with pKis of 6.9 and 7.0, respectively. AC-263093 has the potential for reversing opiate tolerance research. .

AC-263093 (10 mg/kg; i.p.) totally reverses the tolerance to Morphine Sulfate in rats[1].

[1]. David H Malin, et al. Reversal of morphine tolerance by a compound with NPFF receptor subtype-selective actions. Neurosci Lett. 2015 Jan 1:584:141-5. 

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
849459-86-5
Synonyms
AC-263093
Molecular Formula
C8H8Br2N4
Molecular Weight
319.988
Solubility
DMSO : 125 mg/mL (390.65 mM; Need ultrasonic)
Storage
-20°C, sealed storage,away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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