GLPBio

7,3',4'-Trihydroxy-3-benzyl-2H-chromene

Catalog No.: GF18557Purity:>95.00%

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7,3',4'-Trihydroxy-3-benzyl-2H-chromene
Cas No.: 1111897-60-9
1mgIn Stock
$217.00
1

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Description

7,3',4'-Trihydroxy-3-benzyl-2H-chromene is an reversible noncompetitive neuraminidase (NA) inhibitor. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be isolated from the dried heartwood of Caesalpinia sappan L. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene has potent NAs inhibitory activities with IC50 values of 34.6 碌M [H1N1], 39.5 碌M [H3N2], and 50.5碌M [H9N2], respectively. 7,3',4'-Trihydroxy-3-benzyl-2H-chromene can be used for the research of influenza virus.

7,3',4'-Trihydroxy-3-benzyl-2H-chromene (Compound 11) has potent NAs inhibitory activities with IC50 values of 34.6 碌M [H1N1], 39.5 碌M [H3N2], and 50.5 碌M [H9N2], respectively[1].

[1]. Hyung Jae Jeong, et al. Homoisoflavonoids from Caesalpinia sappan displaying viral neuraminidases inhibition. Biol Pharm Bull. 2012;35(5):786-90.  

[2]. Huanxin Zhao, et al. A new homoisoflavan from Caesalpinia sappan. J Nat Med. 2008 Jul;62(3):325-7. 

Product Documents

Purity:>95.00%Appearance:A solid

Chemical Properties

CAS No.
1111897-60-9
Molecular Formula
C16H14O4
Molecular Weight
270.28
Solubility
DMSO : 100 mg/mL (369.99 mM; Need ultrasonic)
Storage
2-8°C, sealed storage,away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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