GLPBio

4-((4-(Aminomethyl)benzyl)oxy)-6-chloropyrimidin-2-amine

Catalog No.: GF29351
COASDSData Sheet
SNAP-fusion protein ligand-1 (Compound 1i) is aLigand for Target Protein forPROTAC.

Products are for research use only. Not for human use. We do not sell to patients.

4-((4-(Aminomethyl)benzyl)oxy)-6-chloropyrimidin-2-amine
Cas No.: 913817-45-5
100mgIn Stock
$70.00
1
250mgIn Stock
$131.00
1
500mgIn Stock
$208.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

SNAP-fusion protein ligand-1 (Compound 1i) is aLigand for Target Protein forPROTAC. SNAP-fusion protein ligand-1 can be used for synthesis ofPROTACVHL-SNAP2-5C[1].

References:
[1].Pol SA, et al. Induced degradation of SNAP-fusion proteins. RSC Chem Biol. 2024 Oct 21;5(12):1232–47.

Product Documents

Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
913817-45-5
Molecular Formula
C12H13ClN4O
Molecular Weight
264.71
Solubility
DMSO : 35 mg/mL(132.22 mM; Need ultrasonic)
Storage
4°C, stored under nitrogen, away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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