GLPBio

1-((4-Nitrophenyl)sulfonyl)piperidine

Catalog No.: GF47600Purity:>95.00%
COASDSData Sheet

Products are for research use only. Not for human use. We do not sell to patients.

1-((4-Nitrophenyl)sulfonyl)piperidine
Cas No.: 64268-93-5
250mgIn Stock
$29.00
1
1gIn Stock
$59.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    31, 1291–1307 (2021)

Description

VP-4604 is a potent anti-methicillin-resistant Staphylococcus aureus (MRSA) agent. VP-4604 exhibits significant microbial growth inhibition toward Staphylococcus aureus (ATCC 43300) with MIC of 4-8 碌g/mL. VP-4604 inhibits the growth of methicillin鈥恟esistant Staphylococcus aureus with growth inhibition >95%.

VP-4604 (2.5 mM, 18 hours) inhibits drug-resistant S. aureus and P. aeruginosa with growth inhibiton (%) GI >95%[1].
VP-4604 shows low cytotoxicity with a CC50 value >118.4 mM towards HEK-293 (human embryonic kidney) ATCC CRL鈥?573 and an HC10 vaule >118.4 渭M towards RBC (human red blood cells) [1].
VP-4604 (2.5 mM) is tolerated by mammalian cells (HaCaT, lymphocytes) with the inhibition growth (%) of 44.1% and >50%, respectively[1].

[1]. Vitalii Palchykov, et al. Antimicrobial action of arylsulfonamides bearing (aza)norbornane and related motifs: evaluation of new promising anti-MRSA agents. Medicinal Chemistry Research. 2022. 31: 284-292.

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
64268-93-5
Molecular Formula
C11H14N2O4S
Molecular Weight
270.31
Solubility
DMSO : 25 mg/mL (92.49 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at RT，sealed storage， away from moisture
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

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