7-Deazaguanosine-5'-Triphosphate is a guanosine triphosphate analog which lacks a nitrogen at the N7 position of the nucleobase. Replacement of this nitrogen atom with a carbon atom results in diminished structure of the major groove in DNA and may disrupt base stacking, but does not interfere with Watson-Crick base pairing. This is desirable for applications such as amplification and sequencing of GC-rich nucleic acid sequences.
7-Deazaguanosine-5'-Triphosphate
Catalog No.: GN20032Purity:>90.00%
Products are for research use only. Not for human use. We do not sell to patients.
1µmoleQuote
$230.00
5µmoleQuote
$1,119.00
10µmoleQuote
$2,116.00
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1µmole | $230.00 | Quote | -- | |
| 5µmole | $1,119.00 | Quote | -- | |
| 10µmole | $2,116.00 | Quote | -- |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>90.00%Appearance:A solid
Chemical Properties
Purity
>90.00%
Extinction Coefficient
9,145 Lmol-1cm-1 at 259 nm
Formula
C11H17N4O14P3 (free acid)
M.Wt
522.10 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2O
Storage
-20°C or below
Synonyms
7-Deaza-GTP
Backbone
5'-Triphosphate
Base Analog
Guanosine
Sugar Type
RNA
Nucleotide Category
Base Modified RNA
Applications
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Reviews
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