The nucleoside analogue 6-thio-2'-deoxyguanosine (6-thio-dG) is a substrate for telomerase and is incorporated into de novo synthesized telomeres. This results in modified telomeres, leading to telomere dysfunction in cells expressing telomerase, such as cancer cells.
6-Thio-2'-deoxyguanosine-5'-Triphosphate
Catalog No.: GN20092Purity:>90.00%
Products are for research use only. Not for human use. We do not sell to patients.
1µmoleIn Stock
$589.00
1
5µmoleIn Stock
$2,763.00
1
10µmoleIn Stock
$5,409.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1µmole | $589.00 | In Stock | 1 | |
| 5µmole | $2,763.00 | In Stock | 1 | |
| 10µmole | $5,409.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>90.00%Appearance:A solid
Chemical Properties
Purity
>90.00%
Extinction Coefficient
24,800 Lmol-1cm-1 at 341 nm
Formula
C10H16N5O12P3S (free acid)
M.Wt
523.20 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2O
Storage
-20°C or below
Synonyms
6-Thio-dGTP
Backbone
5'-Triphosphate
Base Analog
Guanosine
Sugar Type
DNA
Nucleotide Category
Base Modified DNA
Applications
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Reviews
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