GLPBio

5-Hydroxymethyl-2'-deoxycytidine-5'-Triphosphate

Catalog No.: GN20098Purity:>90.00%
COASDSData Sheet

Products are for research use only. Not for human use. We do not sell to patients.

5-Hydroxymethyl-2'-deoxycytidine-5'-Triphosphate
1µmoleQuote
$183.00
5µmoleIn Stock
$879.00
1
10µmoleIn Stock
$1,551.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Methylated deoxycytidine analogs are well studied epigenetic modifications. 5-Hydroxymethyl-2'-deoxycytidine has recently been discovered in mammalian genomic DNA, but is substantially depleted in many types of human cancers. A strong inverse relationship has been demonstrated between the proliferation rate of cells and the global level of 5-hydroxymethyl-2'-deoxycytidine in both porcine and rat tissues, but no such relationship was observed for 5-formyl-2'-deoxycytidine and 5-carboxyl-2'-deoxycytidine.

Product Documents

Purity:>90.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

Purity
>90.00%
Extinction Coefficient
7,700 Lmol-1cm-1 at 275 nm
Formula
C10H18N3O14P3 (free acid)
M.Wt
497.10 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2O
Storage
-20°C or below
Synonyms
5-hme-dCTP, 5-hmdCTP, 5-Hydroxymethyl-dCTP
Backbone
5'-Triphosphate
Base Analog
Cytidine
Sugar Type
DNA
Nucleotide Category
Base Modified DNA
Applications
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies

Reviews

Review for 5-Hydroxymethyl-2'-deoxycytidine-5'-Triphosphate

Rating: 5
  • 5 Star100%
  • 4 Star0%
  • 3 Star0%
  • 2 Star0%
  • 1 Star0%