5-Hydroxymethyl-2'-deoxycytidine-5'-Triphosphate |
Catalog No.GN20098
One-Click Copy Product Info
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Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Methylated deoxycytidine analogs are well studied epigenetic modifications. 5-Hydroxymethyl-2'-deoxycytidine has recently been discovered in mammalian genomic DNA, but is substantially depleted in many types of human cancers. A strong inverse relationship has been demonstrated between the proliferation rate of cells and the global level of 5-hydroxymethyl-2'-deoxycytidine in both porcine and rat tissues, but no such relationship was observed for 5-formyl-2'-deoxycytidine and 5-carboxyl-2'-deoxycytidine.
| purity | >90.00% | Extinction Coefficient | 7,700 Lmol-1cm-1 at 275 nm |
| Formula | C10H18N3O14P3 (free acid) | M.Wt | 497.10 g/mole (free acid) |
| Salt Form | Li+ | Concentration | 100 mM |
| Buffer | H2O | Storage | -20°C or below |
| Synonyms | 5-hme-dCTP, 5-hmdCTP, 5-Hydroxymethyl-dCTP | Backbone | 5'-Triphosphate |
| Base Analog | Cytidine | Sugar Type | DNA |
| Nucleotide Category | Base Modified DNA | ||
| Applications | Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies | ||
Review for 5-Hydroxymethyl-2'-deoxycytidine-5'-Triphosphate
Average Rating: 5 (Based on Reviews and 10 reference(s) in Google Scholar.)