GLPBio

5-Carboxy-2'-deoxycytidine-5'-Triphosphate

Catalog No.: GN20100Purity:>90.00%
COASDSData Sheet

5-Carboxy-dCTP is a dCTP analog recently found to play a role in epigenetic regulation.

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5-Carboxy-2'-deoxycytidine-5'-Triphosphate
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Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

5-Carboxy-dCTP is a dCTP analog recently found to play a role in epigenetic regulation. In addition, the carboxylic acid may be used as a crosslinker to react with amine-containing compounds and surfaces in the presence of an activating agent such as EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride).

Product Documents

Purity:>90.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

Purity
>90.00%
Extinction Coefficient
7,580 Lmol-1cm-1 at 279 nm
Formula
C10H16N3O15P3 (free acid)
M.Wt
511.20 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2O
Storage
-20°C or below
Synonyms
5-Carboxy-dCTP, 5-cadCTP
Backbone
5'-Triphosphate
Base Analog
Cytidine
Sugar Type
DNA
Nucleotide Category
Base Modified DNA
Applications
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies

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