2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddATP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.
2',3'-Dideoxyadenosine-5'-O-(1-Thiotriphosphate)
Catalog No.: GN20162Purity:>90.00%
Products are for research use only. Not for human use. We do not sell to patients.
1µmoleIn Stock
$183.00
1
5µmoleIn Stock
$855.00
1
10µmoleIn Stock
$1,507.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1µmole | $183.00 | In Stock | 1 | |
| 5µmole | $855.00 | In Stock | 1 | |
| 10µmole | $1,507.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>90.00%Appearance:A solid
Chemical Properties
Purity
>90.00%
Extinction Coefficient
15,400 Lmol-1cm-1 at 258 nm
Formula
C10H16N5O10P3S (free acid)
M.Wt
491.20 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2O
Storage
-20°C or below
Synonyms
Alpha Thiol ddATP, 1-Thio-ddATP
Backbone
5'-O-(1-Thiotriphosphate)
Base Analog
Adenosine
Sugar Type
2'-3'-Dideoxy
Nucleotide Category
Phosphate Modified
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