GLPBio

IRFI-165

Catalog No.: GC79190Purity:>98.00%
IRFI-165 is a potent and selective A 1 adenosine receptor antagonist with a K i of 7.9 nM for rat A 1 AR.

Products are for research use only. Not for human use. We do not sell to patients.


IRFI-165
Cas No.: 191349-26-5
5mgIn Stock
$61.00
1
10mgIn Stock
$98.00
1
25mgIn Stock
$174.00
1
50mgIn Stock
$279.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

IRFI-165 is a potent and selective A 1 adenosine receptor antagonist with a K i of 7.9 nM for rat A 1 AR. IRFI-165 exhibies high selectivity versus A 2A and A 3 receptors. IRFI-165 induces antidepressant activity in vivo. IRFI-165 can be used for the research of psychiatric and neurological disorders [1].

References:
[1]. Hess S. Recent advances in adenosine receptor antagonist research. Expert Opinion on Therapeutic Patents, 2001, 11(10): 1533-1561.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
191349-26-5
Molecular Formula
C16H18N4
Molecular Weight
266.35
Solubility
DMSO: 12.5 mg/mL (46.93 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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