GLPBio

Iso-OMPA

Catalog No.: GC75146Purity:>99.00%Synonyms: Tetraisopropyl pyrophosphoramide
Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE).

Products are for research use only. Not for human use. We do not sell to patients.


Iso-OMPA
Cas No.: 513-00-8
10mM (in 1mL DMSO)In Stock
$277.00
1
5 mgIn Stock
$252.00
1
10 mgIn Stock
$405.00
1

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Description

Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective inhibitor of the irreversible butyrylcholinesterase (BuChE). Iso-OMPA enhances soman toxicity in rats associated with the inhibition of plasma carboxylesterase (CarbE)[1][2][3].

References:
[1]. Rodríguez-Fuentes G, et al. Characterization of cholinesterase activity from different tissues of Nile tilapia (Oreochromis niloticus). Mar Environ Res. 2004 Aug-Dec;58(2-5):505-9.
[2]. X Norel, et al. Degradation of acetylcholine in human airways: role of butyrylcholinesterase. Br J Pharmacol. 1993 Apr;108(4):914-9.
[3]. Z Grubic, et al. Iso-OMPA-induced potentiation of soman toxicity in rat correlates with the inhibition of plasma carboxylesterases. Arch Toxicol. 1988;62(5):398-9.

Product Documents

Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
513-00-8
Synonyms
Tetraisopropyl pyrophosphoramide
Molecular Formula
C12H32N4O3P2
Molecular Weight
342.36
Solubility
DMSO: 100 mg/mL (292.09 mM; Need ultrasonic); H2O: 10 mg/mL (29.21 mM; Need ultrasonic)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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