(7RS)-Nivegacetor is the racemate of Nivegacetor. Nivegacetor is a potent and selective γ-secretase modulator. It reduces Aβ42 production and can be used in Alzheimer's disease research [1].
References:
[1]. Tariot P N, et al. Safety and efficacy of crenezumab in cognitively unimpaired carriers of the PSEN1Glu280Ala mutation at risk for autosomal-dominant Alzheimer's disease in Colombia (API ADAD Colombia Trial): a phase 2, randomised, double-blind, placebo-controlled trial[J]. The Lancet Neurology, 2026, 25(2): 147-159.
References:
[1]. Tariot P N, et al. Safety and efficacy of crenezumab in cognitively unimpaired carriers of the PSEN1Glu280Ala mutation at risk for autosomal-dominant Alzheimer's disease in Colombia (API ADAD Colombia Trial): a phase 2, randomised, double-blind, placebo-controlled trial[J]. The Lancet Neurology, 2026, 25(2): 147-159.