Acetomycin (Synonyms: (–)-Acetomycin, NSC 350598) |
| カタログ番号GC46783 |
γ-ラクトン微生物代謝産物
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Cas No.: 510-18-9
Sample solution is provided at 25 µL, 10mM.
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Acetomycin is a γ-lactone microbial metabolite originally isolated from S. ramulosus that has anticancer activity.1 It inhibits proliferation of HCT-8 human colon and L1210 mouse leukemia cancer cells (IC50s = 1.5 and 2.2 µg/ml, respectively)
1.Mamber, S.W., Mitulski, J.D., Hamelehle, K.L., et al.Biological effects of acetomycin. I. Activity against tumor cells in vitro and in vivoJ. Antibiot. (Tokyo)49(1)73-76(1987)
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