Cancer Biology
- Cat.No. 商品名 インフォメーション
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GC49140
α-Conotoxin ImI (trifluoroacetate salt)
A conotoxin and an antagonist of α7 nAChRs
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GC52338
α-Conotoxin PnIA (trifluoroacetate salt)
A peptide antagonist of α3β2-subunit containing and α7 nAChRs
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GC49838
α-Cortolone
A metabolite of cortisol
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GC40702
α-D-Galactopyranosylphenyl isothiocyanate
α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.
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GC45207
α-hydroxy Farnesyl Phosphonic Acid
α-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase).
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GC41499
α-Phellandrene
α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities.
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GC49467
β-Aescin
A triterpenoid saponin with diverse biological activities
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GC40789
β-Cembrenediol
β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate.
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GC48299
β-D-Ribofuranose 1,2,3,5-tetraacetate
A precursor in the synthesis of nucleosides
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GC48998
β-Defensin-1 (human) (trifluoroacetate salt)
An antimicrobial peptide
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GC45604
β-Rubromycin
β-ルブロマイシンは、ヒト免疫不全ウイルス 1 (HIV-1) RNA 指向 DNA ポリメラーゼ (逆転写酵素) の強力かつ選択的な阻害剤です。
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GC52404
γ-Glu-Phe (trifluoroacetate salt)
A dipeptide with metabolism-altering activity
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GC41109
δ12-Prostaglandin J2
δ12-プロスタグランジン J2 (δ12-PGJ2) は、さまざまな腫瘍細胞の増殖に対する抗増殖効果を持つシクロペンテノン プロスタグランジン (PG) です。 δ12-プロスタグランジン D2 の天然の脱水生成物であるプロスタグランジン J2 は、カスパーゼ活性化を介して HeLa 細胞のアポトーシスを誘導することができます。
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GC48532
ε-Rhodomycinone
A bacterial metabolite and precursor to rhodomycin D
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GC41669
(±)-Enterolactone
(±)-エンテロラクトンは、食物リグナンに由来する哺乳動物のリグナンとして知られる生理活性フェノール代謝産物です。 (±)-エンテロラクトンには、エストロゲン特性と抗乳がん活性があります。 (±)-エンテロラクトンは、DNA修復の障害とアポトーシスの増加により、ヒト乳癌細胞株の放射線増感剤です。
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GC41671
(±)-Equol 4'-sulfate (sodium salt)
(±)-Equol 4'-sulfate is a gut-mediated phase II metabolite of the isoflavonoid phytoestrogen (±)-equol.
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GC46000
(•)-Drimenol
A sesquiterpene alcohol
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GC48635
(-)-Cryptopleurine
An alkaloid with diverse biological activities
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GC45250
(-)-L-threo-PDMP (hydrochloride)
(-)-L-threo-PDMP is an enhancer of ganglioside biosynthesis.
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GC45251
(-)-Neplanocin A
S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine.
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GC45253
(-)-Viriditoxin
(-)-Viriditoxin is a mycotoxin originally isolated from A.
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GC48508
(4-Carboxybutyl-d4)triphenylphosphonium (bromide)
An internal standard for the quantification of (4-carboxybutyl)triphenylphosphonium
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GC46038
(5E)-7-Oxozeaenol
A resorcylic acid lactone
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GC41702
(E)-5-(2-Bromovinyl)uracil
(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo.
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GC49003
(E)-Ajoene
A disulfide with diverse biological activities
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GC41620
(R)-(-)-Mellein
(R)-(-)-メレインは、この麹菌の培養液から分離された抗生物質です。
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GC41741
(S)-α-Methylbenzyl Ricinoleamide
(S)-α-Methylbenzyl ricinoleamide is a fatty acid amide derived from ricinoleic acid and methyl benzylamine.
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GC18787
(±)-Dunnione
(±)-Dunnione is a naturally occurring naphthoquinone with diverse biological activities.
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GC46039
1,2,3,4-Tetrahydrostaurosporine
A mutant EGFR inhibitor
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GA20357
1,2-Dimyristoyl-rac-glycerol
A diacylglycerol
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GC41823
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid.
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GC49294
1-(4-Chlorobenzhydryl)piperazine
An inactive metabolite of meclizine and chlorcyclizine
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GC41986
1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position.
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GC42001
1-Myristoyl-2-hydroxy-sn-glycero-3-PE
1-Myristoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid.
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GC18651
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE
1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid.
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GC46496
1-Stearoyl-2-Arachidonoyl-d8-sn-glycero-3-PC
An internal standard for the quantification of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC
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GC41331
1-Stearoyl-2-hydroxy-sn-glycero-3-PC
1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated 18:0 lysophosphatidylcholine found in plasma and oxidized LDL that is thought to play a role in inflammatory diseases and atherosclerosis.
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GC46498
1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC
An internal standard for the quantification of 1-stearoyl-2-hydroxy-sn-glycero-3-PC
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GC40176
1-Stearoyl-rac-glycerol
1-Stearoyl-rac-glycerol is a monoacylglycerol that contains stearic acid at the sn-1 position.
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GC46412
11β-Prostaglandin F2α-d4
An internal standard for the quantification of 11β-PGF F2α
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GC18637
11β-Prostaglandin F2α
11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.
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GC49310
12-hydroxy Stearic Acid
12-ヒドロキシ ステアリン酸は、構造が単純で費用対効果の高い低分子有機ゲル化剤であり、その金属塩と誘導体は、多くの重要なアプリケーションで役割を果たします。
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GC49759
13C17-Mycophenolic Acid
An internal standard for the quantification of mycophenolic acid
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GC41950
16α-hydroxy Estrone
16α-ヒドロキシ エストロン (16αOHE) は主要なエストラジオール代謝物です。
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GC41942
16,16-dimethyl Prostaglandin A2
16,16-dimethyl PGA2 is a metabolism-resistant analog of PGA2 with a prolonged in vivo half-life.
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GC41300
17β-hydroxy Exemestane
17β-hydroxy Exemestane is the primary active metabolite of exemestane.
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GC45307
17(R)-Resolvin D3
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GC46510
2,3,4-Tri-O-acetyl-β-D-Glucuronide methyl ester
A synthetic intermediate
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GC40947
2,3-Dimethoxy-5-methyl-p-benzoquinone
2,3-ジメトキシ-5-メチル-p-ベンゾキノン (CoQ0) は強力な経口活性ユビキノン化合物であり、牛樟茸に由来します。
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GC48417
2,3-Indolobetulinic glycine amide
A derivative of betulinic acid
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GC46522
2,4-Dichlorobenzenesulfonyl chloride
A heterocyclic building block
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GC46502
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide
An antimicrobial agent
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GC46530
2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline
A mutagenic heterocyclic amine
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GC49362
2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline
A food-derived carcinogen
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GC52029
2-Aminoflubendazole
2-アミノフルベンダゾールはベンズイミダゾールの代謝産物です。
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GC46539
2-Chloroadenine
A heterocyclic building block
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GC48943
2-deoxy-2-fluoro-D-Glucose
A glucose derivative with anticancer activity
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GC49223
2-deoxy-D-Glucose-13C6
An internal standard for the quantification of 2-deoxy-D-glucose
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GC49172
2-hydroxy Estrone
2-ヒドロキシ エストロン (カテコレストロン) は、特定の受容体を介した抗エストロゲン剤です。
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GC42170
2-hydroxy Stearic Acid
2-hydroxy Stearic acid is a naturally occurring hydroxylated fatty acid that has been found in humans and U.
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GC40944
2-hydroxy-6-Methylbenzoic Acid
2-hydroxy-6-Methylbenzoic acid is a constituent of G.
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GC13460
2-Hydroxyestradiol
2-ヒドロキシエストラジオールは、17β-エストラジオールの代謝物であり、エストロゲン活性は最小限であり、抗酸化作用があり、DNA と反応して安定した付加物を形成し、遺伝毒性を発揮します 。
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GC42203
3,4',5-Trismethoxybenzophenone
Resveratrol is a potent phenolic antioxidant found in natural sources that has antiproliferative activity.
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GC49361
3,6-Dimethoxy-9H-xanthen-9-one
A synthetic intermediate
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GC52324
3-(3-Hydroxyphenyl)propionic Acid sulfate
A metabolite of certain phenols and glycosides
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GC48481
3-Acetyl Betulin
A derivative of betulin
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GC48487
3-Acetyl Betulinaldehyde
A triterpene
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GC42260
3-Deazauridine
3-Deazauridine is a nucleoside analog.
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GC45337
3-Hydroxyterphenyllin
3-ヒドロキシテルフェニリンはアスペルギルス・カンジダスの代謝産物です。3-ヒドロキシテルフェニリンは増殖を抑制し、A2780/CP70 および OVCAR-3 細胞に対して細胞毒性を引き起こします。 3-ヒドロキシテルフェニリンは、S 期の停止とアポトーシスを誘導します。 3-ヒドロキシテルフェニリンは、卵巣がんの研究に役立つ可能性があります。
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GC49874
3-Methoxycatechol
A lignan-derived phenol
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GC48488
3-Oxobetulin Acetate
A derivative of betulin
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GC46606
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline
A heterocyclic building block
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GC40045
4-(Dimethylamino)-1-methylpyridinium (iodide)
4-(Dimethylamino)-1-methylpyridinium is a monoquaternary pyridinium salt with anticholinesterase and antiproliferative activities.
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GC48824
4-hydroxy Estrone
エストロンの代謝産物である 4-ヒドロキシ エストロン (4-OHE1) は、酸化的神経毒性に対して強力な神経保護効果があります。
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GC42411
4-hydroxy Nonenal Alkyne
4-hydroxy Nonenal (4-HNE) is a major aldehyde produced during the lipid peroxidation of ω-6 polyunsaturated fatty acids, such as arachidonic acid and linoleic acid.
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GC41530
4-oxo Docosahexaenoic Acid
4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity.
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GC49244
4-oxo Isotretinoin
An active metabolite of isotretinoin
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GC40053
5α,6α-epoxy Cholestanol
An oxysterol and a metabolite of cholesterol produced by oxidation
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GC18826
5'-chloro-5'-Deoxyadenosine (hydrate)
5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis.
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GC42503
5'-deoxy-5-Fluorocytidine
5'-deoxy-5-Fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.
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GC49499
5(Z)-Dodecenoic Acid
5(Z)-ドデセン酸は、COX-I および COX-II に対する阻害活性を持つ内因性代謝産物です。
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GC18542
5,6-dihydro-5-Fluorouracil
5,6-dihydro-5-Fluorouracil (5-FUH2) is formed by the hydrogenation of 5-fluorouracil via the enzyme dihydropyrimidine dehydrogenase (DPD).
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GC40527
5-(Hydroxymethyl)-2'-deoxyuridine
5-(Hydroxymethyl)-2'-deoxyuridine is a nucleoside analog with anticancer and antiviral activities.
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GC46033
5-Heneicosylresorcinol
An alkylresorcinol
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GC52172
5-hydroxy Indole-3-acetic Acid-d6
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GC64610
5-O-Caffeoylshikimic acid
5-O-カフェオイルシキミ酸は、NSCLC の研究に使用できます。
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GC41310
5-Octyl-α-ketoglutarate
In addition to its role in the Krebs cycle, α-ketoglutarate (2-oxoglutarate) has roles as a substrate or modulator of enzymes.
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GC49629
6β-hydroxy Prednisolone
A metabolite of prednisolone
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GC46718
6,7-Dihydro-5H-quinolin-8-one
A synthetic intermediate
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GC49551
6-Chloropurine Riboside
A nucleoside precursor
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GC48721
6-O-Demethyl Griseofulvin
A metabolite of griseofulvin
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GC46736
7-Bromoheptanoic Acid
A building block
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GC49051
7-hydroxy Methotrexate
7-ヒドロキシ メトトレキサートは、メトトレキサートの主要な代謝産物です。
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GC42608
7-hydroxy Methotrexate (sodium salt)
7-hydroxy Methotrexate (7-hydroxy MTX) is a phase I metabolite of MTX, which is converted by hepatic aldehyde oxidases.
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GC52239
7-Ketositosterol
A phytosterol and phytosterol oxidation product
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GC49561
7-Methylguanosine-d3
An internal standard for the quantification of 7-methylguanosine
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GC52142
80-O16B
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GC49347
8Br-HA
An FHIT inhibitor
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GC41642
9(E),11(E),13(E)-Octadecatrienoic Acid
9(E),11(E),13(E)-Octadecatrienoic acid (β-ESA) is a conjugated polyunsaturated fatty acid that is found in plant seed oils and in mixtures of conjugated linolenic acids synthesized by the alkaline isomerization of linolenic acid.
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GC42644
9-Deazaguanine
9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM).