ASB 14780 |
| カタログ番号GC50726 |
ASB 14780 は 4-フェノキシ誘導体で、細胞質ホスホリパーゼ A2α (cPLA2α) 阻害剤であり、IC50 値は 20 nM です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1069046-00-9
Sample solution is provided at 25 µL, 10mM.
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Potent and selective cytosolic phospholipase A2 alpha (cPLA2α) inhibitor (IC50 = 20 nM). Selective for cPLA2α over secreted PLA2α (sPLA2α; exhibits no inhibition at 10 μM). Inhibits cPLA2α-dependent inflammatory responses in vitro in guinea pig and human whole-blood assays. Improves diet-induced liver injury and CCl4-induced hepatic fibrosis in vivo. Orally bioavailable.
Average Rating: 5 (Based on Reviews and 12 reference(s) in Google Scholar.)
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