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BAS00602705

カタログ番号GC79126 Copy One-Click Copy Product Info

BAS00602705 is an E-cadherin inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.

BAS00602705 化学構造

Cas No.: 317321-89-4

サイズ 価格 在庫数 個数
10mM (in 1mL DMSO)
$110.00
在庫あり
5mg
$101.00
在庫あり
10mg
$162.00
在庫あり
25mg
$324.00
在庫あり
50mg
$486.00
在庫あり

Tel:(909) 407-4943 Email: sales@glpbio.com


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カスタマーレビューに基づきます。

Sample solution is provided at 25 µL, 10mM.



Description of BAS00602705

BAS00602705 is an E-cadherin inhibitor. BAS00602705 exerts its function by blocking the trans-interactions of E-cadherin molecules within junctional complexes, without permanently altering E-cadherin expression levels. BAS00602705 significantly impairs invadopodia formation in pancreatic cancer cells. BAS00602705 can be used for the study of anti-invasive therapeutic strategies in cancers characterized by dysregulated E-cadherin-mediated invadopodia activity, such as pancreatic ductal adenocarcinoma (PDAC) [1].

References:
[1]. Dobric A, et al. E-Cadherin Is a Structuring Component of Invadopodia in Pancreatic Cancer. J Cell Mol Med. 2025 May;29(9):e70608.

Chemical Properties of BAS00602705

Cas No. 317321-89-4 SDF
Formula C25H22BrN3O3 M.Wt 492.36
溶解度 DMSO: 100 mg/mL (203.10 mM; Need ultrasonic) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of BAS00602705

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.031 mL 10.1552 mL 20.3103 mL
5 mM 406.2 μL 2.031 mL 4.0621 mL
10 mM 203.1 μL 1.0155 mL 2.031 mL
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In vivo Formulation Calculator (Clear solution) of BAS00602705

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Review for BAS00602705

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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