BAY 707 |
| カタログ番号GC50656 |
BAY 707 は、IC50 が 2.3 nM の、基質競合的で強力かつ選択的な MTH1(NUDT1) の阻害剤です。 BAY 707 は、他の MTH1 化合物よりも優れた薬物動態 (PK) プロファイルを持ち、マウスで十分に許容されますが、in vitro または in vivo での抗がん効果が明らかに欠如しています。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2109805-96-9
Sample solution is provided at 25 µL, 10mM.
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Potent and selective MTH1 inhibitor (IC50 = 2.3 nM). Exhibits no significant activity at 1 μM concentration against a panel of 97 kinases. Cell-permeable and active in vivo. Displays no antitumor activity in vitro or in vivo.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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