Fluorescein-PEG6-NHS esterはフルオレセインを持ち、PEGに基づいたリンカーであり、PROTACの合成に使える[1]。Fluorescein-PEG6-NHS esterは、自己組織化単分子膜の作製に使われ、ペプチドスクリーニング法に応用される[2]。Fluorescein-PEG6-NHS esterは、磁性ナノ粒子の修飾に使われ、よって新規な磁性ナノ粒子-水ゲル複合材料を構築する[3]。
References:
[1] An S, Fu L. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs[J]. EBioMedicine, 2018, 36: 553-562.
[2] Sawada T, Okeya Y, Hashizume M, et al. Screening of peptides recognizing simple polycyclic aromatic hydrocarbons[J]. Chemical Communications, 2013, 49(44): 5088-5090.
[3] Hertle L, Ko H, Gantenbein V, et al. A Covalently Bonded Exchange Coupled Nanomagnet‐Based Hydrogel Composite for Microrobotic Applications[J]. Advanced Intelligent Systems, 2025, 7(7): 2400752.