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Autogramin-2

カタログ番号GC35434

オートグラミン 2 は、飢餓 (IC50 = 0.27 μM) または mTORC1 阻害 (ラパマイシン; IC50 = 0.14 μM) によって誘導されるオートファジーを強力に阻害します。

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Autogramin-2 化学構造

Cas No.: 2375541-45-8

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Sample solution is provided at 25 µL, 10mM.

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Autogramin-2 potently inhibits autophagy induced by either starvation (IC50=0.27 μM) or mTORC1 inhibition (Rapamycin; IC50=0.14 μM)[1].

[1]. Laraia L, et al. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nat Chem Biol. 2019 Jul;15(7):710-720.

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Average Rating: 5 ★★★★★ (Based on Reviews and 18 reference(s) in Google Scholar.)

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