GLPBio

GLP-1 (7-36) acid (human, mouse, rat, porcine, bovine)

Catalog No.: GC92119Purity:>98.00%Synonyms: Glucagon-like Peptide 1 (7-36) acid
COASDSData Sheet
GLP-1 (7-36) acid (human, mouse, rat, porcine, bovine)はホルモンとGLP-1受容体（GLP-1 R）アゴニストGLP-1（7-36）アミドの誘導体である。

製品は研究用途にのみ使用できます。人体には使用できません。患者への販売は行っておりません。

GLP-1 (7-36) acid (human, mouse, rat, porcine, bovine)
1 mgIn Stock
$35.00
1
5 mgIn Stock
$158.00
1
10 mgIn Stock
$280.00
1
25 mgIn Stock
$613.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

引用文献 (Citations)

現在、この製品の引用文献はありません。以下はGlpBio製品を引用した代表的な文献です。
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
  • Nature cover
    Nature
    632, 686–694 (2024)
  • Nature cover
    Nature
    618, 1017–1023 (2023)
  • Nature cover
    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
  • Science cover
    Science
    387(6739) (2025)
  • Science cover
    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
  • Cell Research cover
    Cell Research
    34, 683–706 (2024)
  • Cell Research cover
    Cell Research
    33, 273–287 (2023)
  • Cell Research cover
    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

製品説明 (Description)

Glucagon-like peptide 1 (GLP-1) (7-36) acid is a derivative of the hormone and GLP-1 receptor (GLP-1R) agonist GLP-1 (7-36) amide.1,2 It enhances insulin-induced phosphorylation of Akt in 3T3-L1 adipocytes when used at a concentration of 100 nM in the presence of a dipeptidyl peptidase 4 (DPP-4) inhibitor.2 GLP-1 (7-36) acid (150 ?g/kg) reduces plasma levels of total cholesterol, triglycerides, free fatty acids, LDL, insulin, and leptin, as well as adipose tissue weight, in a mouse model of obesity induced by a high-fat diet. It decreases blood glucose levels, food intake, and gastric emptying in non-obese and ob/ob mice when administered at a dose of 3 mg/kg.1

References:
[1]. Fang, X., Du, Z., Duan, C., et al.Beinaglutide shows significantly beneficial effects in diabetes/obesity-induced nonalcoholic steatohepatitis in ob/ob mouse modelLife Sci.270:118966(2021).
[2]. Zhang, F., Chen, Z., Wu, D., et al.Recombinant human GLP-1 beinaglutide regulates lipid metabolism of adipose tissues in diet-induced obese miceiScience24(12)103382(2021).

製品資料 (Product Documents)

Purity:>98.00%Appearance:A solid
COASDSData Sheet

化学的性質 (Chemical Properties)

同義語
Glucagon-like Peptide 1 (7-36) acid
化学名
L-histidyl-L-alanyl-L-α-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-α-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysylglycyl-L-arginine, monoacetate
SMILES
OC(CC[C@H](NC([C@@H](NC([C@H](CC1=CN(C=N1)[H])N[H])=O)C)=O)C(NCC(N[C@@]([H])([C@@H](C)O[H])C(N[C@H](C(N[C@@]([H])([C@@H](C)O[H])C(N[C@@H](CO[H])C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CO[H])C(N[C@@H](CO[H])C(N[C@@H](CC(C=C2)=CC=C2O[H])C(N[C@H](C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CCC(N[H])=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN[H])C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@](C(N[C@H](C(N[C@@H](CC3=CN([H])C4=C3C=CC=C4)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CCCCN[H])C(NCC(N[C@@H](CCC/N=C(N)\N[H])C(O)=O)=O)=O)=O)=O)CC(C)C)=O)=O)C)=O)([H])[C@H](CC)C)=O)CC5=CC=CC=C5)=O)=O)=O)C)=O)C)=O)=O)=O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)=O)=O)=O.CC(O)=O
分子式
C149H225N39O46 ? C2H4O2
分子量
3358.7
溶解性
DMSO: Sparingly soluble: 1-10 mg/ml,PBS (pH 7.2): Slightly soluble: 0.1-1 mg/ml
保存条件
-20°C
一般的な注意事項
製品の溶解性データに基づいて適切な溶媒を選択してください。調製後は、凍結融解の繰り返しを避けるため、ストック溶液を小分けしてください。
ストック溶液は、-80°Cで保存する場合は6か月以内、-20°Cで保存する場合は1か月以内に使用してください。
溶解性を高めるには、チューブを37°Cに温め、適切な時間超音波処理してください。
配送条件
評価用サンプルは保冷剤とともに発送します。その他の容量は室温で発送し、ご要望に応じて保冷剤を同梱します。

計算ツール (Calculators)モル濃度 / 希釈 / 分子量 / 単位変換 / in vivo製剤 / 溶解度

g/mol

Reviews

Review for GLP-1 (7-36) acid (human, mouse, rat, porcine, bovine)

Rating: 5
  • 5 Star100%
  • 4 Star0%
  • 3 Star0%
  • 2 Star0%
  • 1 Star0%